Silence Therapeutics plc ( SLN ) NASDAQ Global Market

Cena: 5.76 ( -0.78% )

Aktualizacja 06-26 17:30
NASDAQ Global Market
Branża: Biotechnology

Notowania:


Informacje o spółce:
Sektor: Zdrowie
Branża: Biotechnology
Zatrudnienie: 109
Giełda: NASDAQ Global Market
Ilość akcji w obrocie: 89%
Ilość akcji: 37 073 277
Debiut giełdowy: 2020-09-08
WWW: https://www.silence-therapeutics.com
CEO: Mr. Craig A. Tooman M.B.A.
Adres: 72 Hammersmith Road
Siedziba: W14 8TH London
ISIN: US82686Q1013
Opis firmy:

Silence Therapeutics Plc, firma biotechnologiczna, koncentruje się na odkrywaniu i rozwoju nowych terapeutycznych kwasu rybonukleinowego (RNA) w hematologii, sercowo -naczyniowych i innych przypadkach rzadkich i metabolicznych. Platforma firmy obejmuje platformę odkrywania oligonukleotydów mRNAi Galnac zaprojektowaną w celu dokładnego ukierunkowania na określone geny związane z chorobą w wątrobie. Projektuje krótkie zakłócające cząsteczki RNA w celu wykorzystania naturalnego mechanizmu interferencji RNA w organizmie oraz degradujących cząsteczki RNA, które kodują specyficzne ukierunkowane białka związane z chorobą w komórce. Firma opracowuje różnych kandydatów na produkty, w tym SLN360, który jest badaniami klinicznymi w fazie I w leczeniu choroby sercowo -naczyniowej wysokim lipoproteiną; SLN124, który jest w badaniach klinicznych fazy I w leczeniu talasemii zależnej od nietransfuzji oraz badań klinicznych fazy I w leczeniu zespołu szpikowego; i SLN124 do leczenia policythemii vera. Ma umowy o współpracy z AstraZeneca PLC w celu odkrycia, rozwijania i komercjalizacji małych zakłócających terapeutyków RNA w leczeniu chorób sercowo -naczyniowych, nerek, metabolicznych i oddechowych; oraz Mallinckrodt Pharma IP Trading DAC w celu opracowania i komercjalizacji celów leków RNAi zaprojektowanych w celu uciszczenia kaskady uzupełniającej w zaburzeniach za pośrednictwem uzupełniania. Firma współpracuje również z Hansoh Pharmaceutical Group Company ograniczoną w celu opracowania siRNA dla trzech nieujawnionych celów wykorzystujących platformę MRNAi Gold Silence. Firma była wcześniej znana jako SR Pharma Plc i zmieniła nazwę na Silence Therapeutics PLC w maju 2007 r. Silence Therapeutics Plc ma siedzibę w Londynie w Wielkiej Brytanii.

Wskaźniki finansowe
Kapitalizacja (USD) 271 810 279
Aktywa: 169 383 000
Cena: 5.76
Wskaźnik Altman Z-Score: 0.3
Słaby (wysokie ryzyko bankructwa)
Dywidenda: 0
P/E: -3.8
Ilość akcji w obrocie: 89%
Średni wolumen: 212 322
Ilość akcji 47 230 283
Wskaźniki finansowe
Przychody TTM 16 245 000
Zobowiązania: 74 868 000
Przedział 52 tyg.: 1.97 - 22.465
Piotroski F-Score: 3
Słaby (niska jakość finansowa)
EPS: -1.5
P/E branży: 26.1
Beta: 1.29
Raport okresowy: 2025-08-15
WWW: https://www.silence-therapeutics.com
Zarząd
Imie i Nazwisko Stanowisko Wynagrodzenie Rok urodzenia
Ms. Rhonda L. Hellums Chief Financial Officer & Secretary 919 991 1973
Dr. Steven J. Romano M.D. Head of Research & Development 671 971 1959
Mr. Craig A. Tooman M.B.A. President, Chief Executive Officer & Executive Director 1 510 586 1965
Dr. Barbara A. Ruskin J.D., Ph.D. Senior Vice President and Chief Intellectual Property & Innovation Officer 0 1960
Dr. Eric Floyd M.B.A., M.S., Ph.D. Senior Vice President of Regulatory Affairs & Quality Assurance 0 1963
Mr. Curtis Rambaran M.D. Chief Medical Officer 0 0
Dr. Marie Wikstrom Lindholm Ph.D. Chief Scientific Officer 0 0
Ms. Gem Gokmen Hopkins Head of IR & Corporate Communications 0 0
Mr. J.P. Gabriel Chief Technical Operations Officer 0 0
Wiadomości dla Silence Therapeutics plc
Tytuł Treść Źródło Aktualizacja Link
Silence Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported its financial results for the first quarter ended March 31, 2025, and reviewed recent business highlights. “Silence delivered another strong quarter focused on clinical and operational execution,” said Craig Tooman, President and Chief Executive Officer at Silence. “We remain focused on advancing enr. businesswire.com 2025-05-08 12:00:00 Czytaj oryginał (ang.)
Silence Therapeutics Welcomes Tim McInerney to Board of Directors LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced the appointment of Tim McInerney to the Company's Board of Directors, effective immediately. Mr. McInerney will stand for re-appointment to the Silence Board at the Annual General Meeting (“AGM”) in June 2025. “We are thrilled to welcome Tim to the Silence Board,” said Iain Ross, Chairman of the Sil. businesswire.com 2025-05-06 11:45:00 Czytaj oryginał (ang.)
Silence Therapeutics to Webcast Presentation at the Leerink Partners Global Healthcare Conference LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that management will present a company overview at the Leerink Partners Global Healthcare Conference on Wednesday, March 12th at 1:00 p.m. ET. The live webcast can be accessed via the Investors section of the Silence website at www.silence-therapeutics.com. An archived replay of the webcast will be. businesswire.com 2025-03-05 10:00:00 Czytaj oryginał (ang.)
Silence Therapeutics (SLN) Upgraded to Buy: Here's What You Should Know Silence Therapeutics (SLN) has been upgraded to a Zacks Rank #2 (Buy), reflecting growing optimism about the company's earnings prospects. This might drive the stock higher in the near term. zacks.com 2025-03-04 15:05:32 Czytaj oryginał (ang.)
Silence Therapeutics plc (SLN) Q4 2024 Earnings Call Transcript Silence Therapeutics plc (NASDAQ:SLN ) Q4 2024 Earnings Call February 27, 2025 8:00 AM ET Company Participants Gem Hopkins - Vice President, Investor Relations and Corporate Communications Craig Tooman - President and Chief Executive Officer Rhonda Hellums - Chief Financial Officer Steven Romano - Chief R&D Officer Conference Call Participants Mike Ulz - Morgan Stanley Kostas Biliouris - BMO Capital Markets Richard Law - Goldman Sachs Keay Nakae - Chardan Myles Minter - William Blair Gem Hopkins Good morning and good afternoon, everyone. Thank you for joining us today. seekingalpha.com 2025-02-28 13:59:32 Czytaj oryginał (ang.)
Silence Therapeutics Reports Full Year 2024 Financial Results and Provides Business Update LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported its financial results for the full year ended December 31, 2024, and provided a business update. “2024 was marked by strong clinical execution and pipeline advancement, highlighting the broad potential of our mRNAi GOLD™ platform to silence disease causing genes,” said Craig Tooman, President and CEO. businesswire.com 2025-02-27 09:30:00 Czytaj oryginał (ang.)
Silence Therapeutics Presents Promising Phase 1 Data in Polycythemia Vera Patients at the American Society of Hematology (ASH) Annual Meeting LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”) (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced additional results from the Phase 1 open label portion of the SANRECO study of divesiran, a siRNA targeting TMPRSS6, in patients with polycythemia vera (PV) were presented at the American Society of Hematology (ASH) Annual Meeting being held in San Diego, California. “Additional divesiran data pres. businesswire.com 2024-12-09 09:30:00 Czytaj oryginał (ang.)
Silence Therapeutics to Participate in Fireside Chat at Piper Sandler 36th Annual Healthcare Conference LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical stage biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced the Company will participate in a fireside chat at the Piper Sandler 36th Annual Healthcare Conference on Wednesday, December 4th at 10:00 a.m. ET. The live webcast can be accessed via the Investors section of the Silence website at www.sile. businesswire.com 2024-11-26 10:00:00 Czytaj oryginał (ang.)
SLN Stock Down Despite Cholesterol Drug Lowering Lipoprotein Levels Silence Therapeutics stock falls despite lowering lipoprotein levels in a phase II study of zerlasiran likely due to concerns regarding its competitive profile. zacks.com 2024-11-20 14:06:17 Czytaj oryginał (ang.)
Silence Therapeutics' Zerlasiran Has Competitive Concerns: Analyst On Monday, Silence Therapeutics plc SLN presented end-of-treatment data from its Phase 2 ALPACAR-360 study of zerlasiran in atherosclerotic cardiovascular disease (ASCVD) patients with high lipoprotein(a) [Lp(a)] levels (≥125 nmol/L). benzinga.com 2024-11-19 17:34:42 Czytaj oryginał (ang.)
Silence Therapeutics Presents Late-Breaking Phase 2 Zerlasiran Data at 2024 American Heart Association (AHA) Annual Meeting LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical stage biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today presented end-of-treatment data from its Phase 2 ALPACAR-360 study of zerlasiran, a short interfering RNA (siRNA), in atherosclerotic cardiovascular disease (ASCVD) patients with high lipoprotein(a) [Lp(a)] levels (≥125 nmol/L). These data were presen. businesswire.com 2024-11-18 16:30:00 Czytaj oryginał (ang.)
Silence Therapeutics' RNAi Pipeline: Zerlasiran's Game-Changer Potential Is A 'Buy' Silence Therapeutics focuses on RNA interference therapies, with its lead candidates targeting cardiovascular and hematological diseases via the mRNAi GOLD platform. Zerlasiran, the company's main value driver, aims to reduce lipoprotein(a) levels, potentially lowering cardiovascular risks in 20-25% of the global population. Divesiran shows promise in early trials for Polycythemia Vera. Early clinical trial data suggests it can effectively regulate red blood cell production. seekingalpha.com 2024-09-08 13:13:46 Czytaj oryginał (ang.)
Silence: Additional siRNA Drug Data Leads To Next Stages Of Development Silence Therapeutics plc's positive results achieved from phase 1 SANRECO study using divesiran for the treatment of patients with polycythemia vera. The global polycythemia vera treatment market size is predicted to reach $45 billion by the end of 2036. Full detailed results from the phase 1 SANRECO study, using divesiran for the treatment of patients with polycythemia vera, are to be presented at an upcoming medical conference before the end of 2024. seekingalpha.com 2024-09-05 18:18:59 Czytaj oryginał (ang.)
Silence Therapeutics to Webcast Presentations at Upcoming September Investor Conferences LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced that management will present company overviews at the following conferences: Morgan Stanley Global Healthcare Conference on Thursday, September 5, 2024 at 5:35pm ET HC Wainwright Global Investment Conference on Tuesday, September 10, 2. businesswire.com 2024-08-27 12:00:00 Czytaj oryginał (ang.)
The 3 Best Gene Editing Stocks to Buy in August 2024 Investing guru Cathie Wood sees precision therapeutics as a massive growth market. She forecasts sales in the category can grow by a compound annual growth rate (CAGR) of 30% through 2030. investorplace.com 2024-08-07 13:00:00 Czytaj oryginał (ang.)
Morgan Stanley Predicts Triple-Digit Rally for These 3 Stocks Wall Street likes to peer into the fog of the future and guess where a stock is headed. While these stock price predictions are based on educated estimates, often based on information and models unavailable to regular investors, they are nonetheless guesses. investorplace.com 2024-07-25 10:08:00 Czytaj oryginał (ang.)
Silence Therapeutics (SLN) Moves 5.8% Higher: Will This Strength Last? Silence Therapeutics (SLN) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock doesn't suggest further strength down the road. zacks.com 2024-07-12 15:11:30 Czytaj oryginał (ang.)
Silence Therapeutics Achieves $2 Million Research Milestone Payment from Hansoh Pharma Collaboration LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), an experienced and innovative biotechnology company committed to transforming peoples' lives by silencing diseases through precision engineered medicines, today announced that it will receive a $2.0 million cash payment from Hansoh Pharmaceutical Group Company Limited (“Hansoh”) following the achievement of a second undisclosed milestone related to the first target under the collaboration. “This represe. businesswire.com 2024-06-24 12:30:00 Czytaj oryginał (ang.)
Silence Therapeutics: PV Data For Consideration After ASCVD Treatment Results Silence Therapeutics plc results from the phase 1 SANRECO study, using divesiran for the treatment of patients with polycythemia vera, expected end of June 2024. The 7 major polycythemia vera markets are expected to reach $68.5 billion by 2034. Positive results achieved in the phase 2 ALPACAR-360 study using zerlasiran for patients with elevated levels of Lp[a] at high risk of ASCVD. seekingalpha.com 2024-06-21 18:31:06 Czytaj oryginał (ang.)
Silence Therapeutics Announces Positive Topline 48-Week Data from Phase 2 Study of Zerlasiran in Patients with Elevated Lipoprotein(a) LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced positive topline 48-week data from the ALPACAR-360 phase 2 study of zerlasiran (SLN360) in 178 subjects with baseline lipoprotein(a), or Lp(a), levels at or over 125 nmol/L at high risk of atherosclerotic cardiovascular disease (ASCVD). businesswire.com 2024-06-20 11:30:00 Czytaj oryginał (ang.)
Silence Therapeutics to Present at Jefferies Global Healthcare Conference LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced the Company will present at the Jefferies Global Healthcare Conference on Thursday, June 6th at 2:30 p.m. ET. The live webcast can be accessed via the Investors section of the Silence website at www.silence-therapeutics.com. An archive. businesswire.com 2024-05-30 12:30:00 Czytaj oryginał (ang.)
Silence Therapeutics Reports First Quarter 2024 Results and Highlights Pipeline Progress LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today reported its financial results for the first quarter ended March 31, 2024 and reviewed recent business highlights. “Silence's first quarter performance reflects another period of solid execution with the continued advancement of both our wholly. businesswire.com 2024-05-16 12:30:00 Czytaj oryginał (ang.)
Silence Therapeutics to Participate in Fireside Chat at H.C. Wainwright 2nd Annual BioConnect Investor Conference LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced the Company will participate in a fireside chat at the H.C. Wainwright 2nd Annual BioConnect Investor Conference on Monday, May 20th at 2:30 p.m. ET. The live webcast can be accessed via the Investors section of the Silence website at. businesswire.com 2024-04-30 12:30:00 Czytaj oryginał (ang.)
Silence Therapeutics Announces Retirement of Alistair Gray from Board of Directors LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN) (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced that Alistair Gray, who has served as an independent member of Silence's Board of Directors (the “Board”) since 2015, informed the Company that he will retire from the Board, effective May 1, 2024. Iain Ross, Silence's Chairman of the. businesswire.com 2024-04-29 12:30:00 Czytaj oryginał (ang.)
Silence Therapeutics (SLN) Surges 5.7%: Is This an Indication of Further Gains? Silence Therapeutics (SLN) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions could translate into further price increase in the near term. zacks.com 2024-04-12 13:26:03 Czytaj oryginał (ang.)
3 Biotech Stocks to Turn $5,000 Into $1 Million: April 2024 Biotech stocks can offer some of the most explosive, exciting opportunities on the market. That is, if you find the right one. investorplace.com 2024-04-11 16:24:46 Czytaj oryginał (ang.)