| JOHNSON & JOHNSON COMMON STOCK USD1.0 |
JNJ
|
177 293 460 |
7.5 |
1 097 113 |
| ABBVIE INC COMMON STOCK USD.01 |
ABBV
|
156 249 141 |
6.6 |
804 993 |
| MERCK & CO. INC. COMMON STOCK USD.5 |
MRK
|
126 649 719 |
5.3 |
1 154 615 |
| THERMO FISHER SCIENTIFIC INC COMMON STOCK USD1.0 |
TMO
|
105 064 894 |
4.4 |
174 009 |
| ABBOTT LABORATORIES COMMON STOCK |
ABT
|
92 547 301 |
3.9 |
793 036 |
| DANAHER CORP COMMON STOCK USD.01 |
DHR
|
82 524 096 |
3.5 |
303 889 |
| AMGEN INC COMMON STOCK USD.0001 |
AMGN
|
79 383 548 |
3.3 |
244 543 |
| INTUITIVE SURGICAL INC COMMON STOCK USD.001 |
ISRG
|
78 844 098 |
3.3 |
161 695 |
| PFIZER INC COMMON STOCK USD.05 |
PFE
|
75 119 194 |
3.2 |
2 583 191 |
| BOSTON SCIENTIFIC CORP COMMON STOCK USD.01 |
BSX
|
58 676 185 |
2.5 |
670 202 |
| VERTEX PHARMACEUTICALS INC COMMON STOCK USD.01 |
VRTX
|
57 030 831 |
2.4 |
117 633 |
| STRYKER CORP COMMON STOCK USD.1 |
SYK
|
56 220 874 |
2.4 |
156 295 |
| ELEVANCE HEALTH INC COMMON STOCK USD.01 |
ELV
|
53 932 196 |
2.3 |
105 953 |
| MEDTRONIC PLC COMMON STOCK USD.1 |
MDT
|
52 614 355 |
2.2 |
584 539 |
| REGENERON PHARMACEUTICALS COMMON STOCK USD.001 |
REGN
|
50 101 921 |
2.1 |
49 398 |
| BRISTOL MYERS SQUIBB CO COMMON STOCK USD.1 |
BMY
|
48 671 293 |
2.0 |
924 080 |
| GILEAD SCIENCES INC COMMON STOCK USD.001 |
GILD
|
48 302 956 |
2.0 |
567 936 |
| THE CIGNA GROUP COMMON STOCK USD.01 |
CI
|
45 512 775 |
1.9 |
129 500 |
| ZOETIS INC COMMON STOCK USD.01 |
ZTS
|
40 072 163 |
1.7 |
208 005 |
| CVS HEALTH CORP COMMON STOCK USD.01 |
CVS
|
38 605 806 |
1.6 |
572 277 |
| HCA HEALTHCARE INC COMMON STOCK USD.01 |
HCA
|
35 441 307 |
1.5 |
89 548 |
| BECTON DICKINSON AND CO COMMON STOCK USD1.0 |
BDX
|
31 621 674 |
1.3 |
131 746 |
| MCKESSON CORP COMMON STOCK USD.01 |
MCK
|
30 112 707 |
1.3 |
59 128 |
| IQVIA HOLDINGS INC COMMON STOCK USD.01 |
IQV
|
19 371 019 |
0.8 |
83 059 |
| AGILENT TECHNOLOGIES INC COMMON STOCK USD.01 |
A
|
19 185 971 |
0.8 |
133 005 |
| EDWARDS LIFESCIENCES CORP COMMON STOCK USD1.0 |
EW
|
19 127 778 |
0.8 |
274 706 |
| CENCORA INC COMMON STOCK USD.01 |
COR
|
18 395 527 |
0.8 |
81 827 |
| GE HEALTHCARE TECHNOLOGY COMMON STOCK USD.01 |
GEHC
|
18 111 533 |
0.8 |
197 681 |
| IDEXX LABORATORIES INC COMMON STOCK USD.1 |
IDXX
|
17 997 178 |
0.8 |
37 651 |
| CENTENE CORP COMMON STOCK USD.001 |
CNC
|
17 734 528 |
0.7 |
243 272 |
| ALNYLAM PHARMACEUTICALS INC COMMON STOCK USD.01 |
ALNY
|
16 336 797 |
0.7 |
57 662 |
| RESMED INC COMMON STOCK USD.004 |
RMD
|
16 120 589 |
0.7 |
66 971 |
| HUMANA INC COMMON STOCK USD.1666666 |
HUM
|
14 709 972 |
0.6 |
54 970 |
| VEEVA SYSTEMS INC CLASS A COMMON STOCK USD.00001 |
VEEV
|
14 730 872 |
0.6 |
70 007 |
| METTLER TOLEDO INTERNATIONAL COMMON STOCK USD.01 |
MTD
|
14 184 281 |
0.6 |
9 736 |
| BIOGEN INC COMMON STOCK USD.0005 |
BIIB
|
12 708 473 |
0.5 |
66 342 |
| DEXCOM INC COMMON STOCK USD.001 |
DXCM
|
12 537 906 |
0.5 |
181 236 |
| CARDINAL HEALTH INC COMMON STOCK |
CAH
|
12 427 149 |
0.5 |
111 036 |
| ILLUMINA INC COMMON STOCK USD.01 |
ILMN
|
10 815 922 |
0.5 |
72 556 |
| STERIS PLC COMMON STOCK USD75.0 |
STE
|
10 304 594 |
0.4 |
45 154 |
| ZIMMER BIOMET HOLDINGS INC COMMON STOCK USD.01 |
ZBH
|
9 824 038 |
0.4 |
93 714 |
| WEST PHARMACEUTICAL SERVICES COMMON STOCK USD.25 |
WST
|
9 807 096 |
0.4 |
33 205 |
| COOPER COS INC/THE COMMON STOCK USD.1 |
COO
|
9 764 422 |
0.4 |
90 680 |
| WATERS CORP COMMON STOCK USD.01 |
WAT
|
9 658 611 |
0.4 |
27 036 |
| MOLINA HEALTHCARE INC COMMON STOCK USD.001 |
MOH
|
9 073 381 |
0.4 |
26 677 |
| HOLOGIC INC COMMON STOCK USD.01 |
HOLX
|
8 670 982 |
0.4 |
106 236 |
| MODERNA INC COMMON STOCK USD.0001 |
MRNA
|
8 569 325 |
0.4 |
148 438 |
| BAXTER INTERNATIONAL INC COMMON STOCK USD1.0 |
BAX
|
8 568 619 |
0.4 |
232 149 |
| LABCORP HOLDINGS INC COMMON STOCK USD.1 |
LH
|
8 335 714 |
0.4 |
38 440 |
| AVANTOR INC COMMON STOCK USD.01 |
AVTR
|
7 772 133 |
0.3 |
310 141 |
| QUEST DIAGNOSTICS INC COMMON STOCK USD.01 |
DGX
|
7 541 039 |
0.3 |
50 611 |
| INSULET CORP COMMON STOCK USD.001 |
PODD
|
7 420 091 |
0.3 |
31 913 |
| ALIGN TECHNOLOGY INC COMMON STOCK USD.0001 |
ALGN
|
7 203 444 |
0.3 |
32 555 |
| NATERA INC COMMON STOCK |
NTRA
|
6 998 469 |
0.3 |
53 075 |
| TENET HEALTHCARE CORP COMMON STOCK USD.05 |
THC
|
6 927 952 |
0.3 |
44 613 |
| REVVITY INC COMMON STOCK USD1.0 |
RVTY
|
6 916 514 |
0.3 |
56 273 |
| UNITED THERAPEUTICS CORP COMMON STOCK USD.01 |
UTHR
|
6 869 532 |
0.3 |
19 237 |
| SS INST TREAS PLUS MM FUND TRU SS INST TREAS PLUS MM FUND TR |
|
6 474 000 |
0.3 |
6 474 000 |
| VIATRIS INC COMMON STOCK |
VTRS
|
6 183 266 |
0.3 |
542 868 |
| BIOMARIN PHARMACEUTICAL INC COMMON STOCK USD.001 |
BMRN
|
6 095 290 |
0.3 |
86 741 |
| EXACT SCIENCES CORP COMMON STOCK USD.01 |
EXAS
|
5 974 042 |
0.3 |
84 272 |
| UNIVERSAL HEALTH SERVICES B COMMON STOCK USD.01 |
UHS
|
5 985 437 |
0.3 |
27 151 |
| NEUROCRINE BIOSCIENCES INC COMMON STOCK USD.001 |
NBIX
|
5 355 308 |
0.2 |
45 992 |
| INSMED INC COMMON STOCK USD.01 |
INSM
|
5 314 537 |
0.2 |
70 785 |
| BIO TECHNE CORP COMMON STOCK USD.01 |
TECH
|
5 315 335 |
0.2 |
72 004 |
| TELEFLEX INC COMMON STOCK USD1.0 |
TFX
|
5 099 249 |
0.2 |
21 485 |
| CATALENT INC COMMON STOCK USD.01 |
CTLT
|
4 992 768 |
0.2 |
82 321 |
| ROYALTY PHARMA PLC CL A COMMON STOCK |
RPRX
|
4 891 965 |
0.2 |
175 528 |
| INCYTE CORP COMMON STOCK USD.001 |
INCY
|
4 868 212 |
0.2 |
74 392 |
| SAREPTA THERAPEUTICS INC COMMON STOCK USD.0001 |
SRPT
|
4 831 525 |
0.2 |
38 848 |
| VAXCYTE INC COMMON STOCK USD.001 |
PCVX
|
4 757 519 |
0.2 |
42 061 |
| SOLVENTUM CORP COMMON STOCK |
SOLV
|
4 660 024 |
0.2 |
67 157 |
| CHARLES RIVER LABORATORIES COMMON STOCK USD.01 |
CRL
|
4 544 777 |
0.2 |
23 531 |
| ENCOMPASS HEALTH CORP COMMON STOCK USD.01 |
EHC
|
4 411 117 |
0.2 |
45 806 |
| MEDPACE HOLDINGS INC COMMON STOCK USD.01 |
MEDP
|
4 231 748 |
0.2 |
11 971 |
| HENRY SCHEIN INC COMMON STOCK USD.01 |
HSIC
|
4 154 582 |
0.2 |
58 507 |
| CHEMED CORP COMMON STOCK USD1.0 |
CHE
|
3 950 376 |
0.2 |
6 581 |
| DAVITA INC COMMON STOCK USD.001 |
DVA
|
3 886 347 |
0.2 |
24 015 |
| ENSIGN GROUP INC/THE COMMON STOCK USD.001 |
ENSG
|
3 843 580 |
0.2 |
26 000 |
| GLOBUS MEDICAL INC A COMMON STOCK USD.001 |
GMED
|
3 661 088 |
0.2 |
51 427 |
| PENUMBRA INC COMMON STOCK USD.001 |
PEN
|
3 558 879 |
0.2 |
16 838 |
| LANTHEUS HOLDINGS INC COMMON STOCK USD.01 |
LNTH
|
3 505 063 |
0.1 |
31 657 |
| REPLIGEN CORP COMMON STOCK USD.01 |
RGEN
|
3 461 810 |
0.1 |
24 200 |
| HEALTHEQUITY INC COMMON STOCK USD.0001 |
HQY
|
3 381 890 |
0.1 |
39 801 |
| ELANCO ANIMAL HEALTH INC COMMON STOCK |
ELAN
|
3 234 054 |
0.1 |
225 056 |
| INTRA CELLULAR THERAPIES INC COMMON STOCK USD.0001 |
ITCI
|
3 205 985 |
0.1 |
43 418 |
| EXELIXIS INC COMMON STOCK USD.001 |
EXEL
|
3 135 889 |
0.1 |
119 508 |
| HALOZYME THERAPEUTICS INC COMMON STOCK USD.001 |
HALO
|
3 118 957 |
0.1 |
57 812 |
| BIO RAD LABORATORIES A COMMON STOCK USD.0001 |
BIO
|
3 094 437 |
0.1 |
9 073 |
| BRUKER CORP COMMON STOCK USD.01 |
BRKR
|
3 069 257 |
0.1 |
48 411 |
| JAZZ PHARMACEUTICALS PLC COMMON STOCK USD.0001 |
JAZZ
|
3 036 559 |
0.1 |
27 349 |
| GLAUKOS CORP COMMON STOCK USD.001 |
GKOS
|
3 001 973 |
0.1 |
23 085 |
| VIKING THERAPEUTICS INC COMMON STOCK USD.00001 |
VKTX
|
2 981 990 |
0.1 |
45 319 |
| MASIMO CORP COMMON STOCK USD.001 |
MASI
|
2 985 013 |
0.1 |
20 679 |
| INSPIRE MEDICAL SYSTEMS INC COMMON STOCK USD.001 |
INSP
|
2 853 206 |
0.1 |
13 557 |
| CYTOKINETICS INC COMMON STOCK USD.001 |
CYTK
|
2 746 255 |
0.1 |
50 390 |
| REVOLUTION MEDICINES INC COMMON STOCK |
RVMD
|
2 584 345 |
0.1 |
52 506 |
| MERIT MEDICAL SYSTEMS INC COMMON STOCK |
MMSI
|
2 530 038 |
0.1 |
26 487 |
| ACADIA HEALTHCARE CO INC COMMON STOCK USD.01 |
ACHC
|
2 410 985 |
0.1 |
42 350 |
| BLUEPRINT MEDICINES CORP COMMON STOCK USD.001 |
BPMC
|
2 410 482 |
0.1 |
27 191 |
| OPTION CARE HEALTH INC COMMON STOCK USD.0001 |
OPCH
|
2 416 120 |
0.1 |
78 984 |
| IONIS PHARMACEUTICALS INC COMMON STOCK USD.001 |
IONS
|
2 307 794 |
0.1 |
59 741 |
| DENTSPLY SIRONA INC COMMON STOCK USD.01 |
XRAY
|
2 306 118 |
0.1 |
94 397 |
| DOXIMITY INC CLASS A COMMON STOCK USD.001 |
DOCS
|
2 126 364 |
0.1 |
50 676 |
| ALKERMES PLC COMMON STOCK USD.01 |
ALKS
|
2 125 298 |
0.1 |
73 160 |
| ORGANON & CO COMMON STOCK USD.01 |
OGN
|
2 115 292 |
0.1 |
116 867 |
| ULTRAGENYX PHARMACEUTICAL IN COMMON STOCK USD.001 |
RARE
|
2 091 560 |
0.1 |
37 223 |
| INTEGER HOLDINGS CORP COMMON STOCK USD.001 |
ITGR
|
2 009 625 |
0.1 |
15 175 |
| RADNET INC COMMON STOCK USD.0001 |
RDNT
|
2 014 364 |
0.1 |
28 524 |
| TRANSMEDICS GROUP INC COMMON STOCK |
TMDX
|
2 009 632 |
0.1 |
14 971 |
| ROIVANT SCIENCES LTD COMMON STOCK USD.0000001 |
ROIV
|
1 997 822 |
0.1 |
168 735 |
| CRINETICS PHARMACEUTICALS IN COMMON STOCK USD.001 |
CRNX
|
1 961 089 |
0.1 |
36 932 |
| CORCEPT THERAPEUTICS INC COMMON STOCK USD.001 |
CORT
|
1 929 145 |
0.1 |
42 586 |
| ICU MEDICAL INC COMMON STOCK USD.1 |
ICUI
|
1 906 311 |
0.1 |
10 573 |
| CRISPR THERAPEUTICS AG COMMON STOCK CHF.03 |
CRSP
|
1 756 420 |
0.1 |
36 726 |
| HAEMONETICS CORP/MASS COMMON STOCK USD.01 |
HAE
|
1 736 789 |
0.1 |
23 068 |
| BIOHAVEN LTD COMMON STOCK |
BHVN
|
1 701 726 |
0.1 |
32 248 |
| AVIDITY BIOSCIENCES INC COMMON STOCK |
RNA
|
1 687 445 |
0.1 |
36 126 |
| SELECT MEDICAL HOLDINGS CORP COMMON STOCK USD.001 |
SEM
|
1 695 576 |
0.1 |
50 017 |
| ADMA BIOLOGICS INC COMMON STOCK USD.0001 |
ADMA
|
1 636 967 |
0.1 |
99 998 |
| KRYSTAL BIOTECH INC COMMON STOCK USD.00001 |
KRYS
|
1 641 720 |
0.1 |
9 142 |
| PROCEPT BIOROBOTICS CORP COMMON STOCK USD.00001 |
PRCT
|
1 630 231 |
0.1 |
22 335 |
| AXONICS INC COMMON STOCK USD.0001 |
AXNX
|
1 623 065 |
0.1 |
23 114 |
| PRESTIGE CONSUMER HEALTHCARE COMMON STOCK USD.01 |
PBH
|
1 588 082 |
0.1 |
22 661 |
| DENALI THERAPEUTICS INC COMMON STOCK USD.01 |
DNLI
|
1 573 042 |
0.1 |
58 630 |
| TG THERAPEUTICS INC COMMON STOCK USD.001 |
TGTX
|
1 534 267 |
0.1 |
67 204 |
| PERRIGO CO PLC COMMON STOCK EUR.001 |
PRGO
|
1 494 759 |
0.1 |
61 818 |
| AMEDISYS INC COMMON STOCK USD.001 |
AMED
|
1 442 759 |
0.1 |
14 903 |
| ENVISTA HOLDINGS CORP COMMON STOCK USD.01 |
NVST
|
1 393 286 |
0.1 |
78 099 |
| CORVEL CORP COMMON STOCK USD.0001 |
CRVL
|
1 377 184 |
0.1 |
4 299 |
| NUVALENT INC A COMMON STOCK USD.0001 |
NUVL
|
1 382 949 |
0.1 |
13 389 |
| HIMS & HERS HEALTH INC COMMON STOCK USD.0001 |
HIMS
|
1 344 308 |
0.1 |
65 576 |
| BRIDGEBIO PHARMA INC COMMON STOCK |
BBIO
|
1 324 395 |
0.1 |
51 373 |
| LIVANOVA PLC COMMON STOCK GBP1.0 |
LIVN
|
1 330 306 |
0.1 |
24 720 |
| NEOGEN CORP COMMON STOCK USD.16 |
NEOG
|
1 313 744 |
0.1 |
93 705 |
| MADRIGAL PHARMACEUTICALS INC COMMON STOCK USD.0001 |
MDGL
|
1 263 066 |
0.1 |
5 863 |
| ARCELLX INC COMMON STOCK USD.001 |
ACLX
|
1 262 825 |
0.1 |
14 547 |
| EVOLENT HEALTH INC A COMMON STOCK USD.01 |
EVH
|
1 224 729 |
0.1 |
45 143 |
| PTC THERAPEUTICS INC COMMON STOCK USD.001 |
PTCT
|
1 229 309 |
0.1 |
31 408 |
| TWIST BIOSCIENCE CORP COMMON STOCK USD.00001 |
TWST
|
1 232 835 |
0.1 |
26 433 |
| ASTRANA HEALTH INC COMMON STOCK USD.001 |
ASTH
|
1 202 938 |
0.1 |
20 170 |
| AXSOME THERAPEUTICS INC COMMON STOCK USD.0001 |
AXSM
|
1 216 978 |
0.1 |
14 247 |
| XENON PHARMACEUTICALS INC COMMON STOCK |
XENE
|
1 218 515 |
0.1 |
29 179 |
| GUARDANT HEALTH INC COMMON STOCK USD.00001 |
GH
|
1 182 513 |
0.0 |
55 413 |
| VERACYTE INC COMMON STOCK USD.001 |
VCYT
|
1 172 654 |
0.0 |
34 561 |
| ADDUS HOMECARE CORP COMMON STOCK USD.001 |
ADUS
|
1 090 464 |
0.0 |
8 273 |
| TANDEM DIABETES CARE INC COMMON STOCK |
TNDM
|
1 093 676 |
0.0 |
29 274 |
| R1 RCM INC COMMON STOCK USD.01 |
RCM
|
1 078 575 |
0.0 |
75 956 |
| AMICUS THERAPEUTICS INC COMMON STOCK USD.01 |
FOLD
|
1 047 355 |
0.0 |
100 514 |
| MERUS NV COMMON STOCK EUR.05 |
MRUS
|
1 043 869 |
0.0 |
20 009 |
| MYRIAD GENETICS INC COMMON STOCK USD.01 |
MYGN
|
1 039 767 |
0.0 |
41 425 |
| QUIDELORTHO CORP COMMON STOCK USD.001 |
QDEL
|
1 052 780 |
0.0 |
26 001 |
| RHYTHM PHARMACEUTICALS INC COMMON STOCK |
RYTM
|
1 036 451 |
0.0 |
20 630 |
| UFP TECHNOLOGIES INC COMMON STOCK USD.01 |
UFPT
|
1 050 924 |
0.0 |
3 347 |
| AZENTA INC COMMON STOCK USD.01 |
AZTA
|
1 012 961 |
0.0 |
22 258 |
| INARI MEDICAL INC COMMON STOCK USD.001 |
NARI
|
1 009 846 |
0.0 |
23 930 |
| SOTERA HEALTH CO COMMON STOCK USD.01 |
SHC
|
992 157 |
0.0 |
64 384 |
| SURGERY PARTNERS INC COMMON STOCK USD.01 |
SGRY
|
1 003 395 |
0.0 |
31 603 |
| ENOVIS CORP COMMON STOCK USD.001 |
ENOV
|
999 924 |
0.0 |
24 942 |
| CATALYST PHARMACEUTICALS INC COMMON STOCK USD.001 |
CPRX
|
995 735 |
0.0 |
48 243 |
| ARROWHEAD PHARMACEUTICALS IN COMMON STOCK USD.001 |
ARWR
|
988 289 |
0.0 |
51 048 |
| APELLIS PHARMACEUTICALS INC COMMON STOCK USD.0001 |
APLS
|
980 121 |
0.0 |
35 797 |
| AGIOS PHARMACEUTICALS INC COMMON STOCK USD.001 |
AGIO
|
951 256 |
0.0 |
23 044 |
| IDEAYA BIOSCIENCES INC COMMON STOCK |
IDYA
|
948 409 |
0.0 |
31 126 |
| PREMIER INC CLASS A COMMON STOCK USD.01 |
PINC
|
927 300 |
0.0 |
47 873 |
| PROTAGONIST THERAPEUTICS INC COMMON STOCK USD.00001 |
PTGX
|
923 662 |
0.0 |
19 928 |
| CONMED CORP COMMON STOCK USD.01 |
CNMD
|
900 707 |
0.0 |
13 945 |
| VERICEL CORP COMMON STOCK |
VCEL
|
897 990 |
0.0 |
21 335 |
| LONGBOARD PHARMACEUTICALS IN COMMON STOCK USD.0001 |
LBPH
|
889 274 |
0.0 |
15 075 |
| OMNICELL INC COMMON STOCK USD.001 |
OMCL
|
882 630 |
0.0 |
20 656 |
| IOVANCE BIOTHERAPEUTICS INC COMMON STOCK USD.000041666 |
IOVA
|
886 725 |
0.0 |
90 760 |
| AMPHASTAR PHARMACEUTICALS IN COMMON STOCK USD.0001 |
AMPH
|
868 785 |
0.0 |
17 626 |
| GERON CORP COMMON STOCK USD.001 |
GERN
|
844 191 |
0.0 |
203 911 |
| LIGAND PHARMACEUTICALS COMMON STOCK USD.001 |
LGND
|
849 303 |
0.0 |
8 209 |
| LEMAITRE VASCULAR INC COMMON STOCK USD.01 |
LMAT
|
862 338 |
0.0 |
9 359 |
| BEAM THERAPEUTICS INC COMMON STOCK USD.01 |
BEAM
|
838 701 |
0.0 |
31 542 |
| CELLDEX THERAPEUTICS INC COMMON STOCK USD.001 |
CLDX
|
825 039 |
0.0 |
27 247 |
| IRHYTHM TECHNOLOGIES INC COMMON STOCK USD.001 |
IRTC
|
824 415 |
0.0 |
14 230 |
| SUPERNUS PHARMACEUTICALS INC COMMON STOCK USD.001 |
SUPN
|
831 723 |
0.0 |
25 265 |
| NEOGENOMICS INC COMMON STOCK USD.001 |
NEO
|
803 548 |
0.0 |
58 186 |
| INTELLIA THERAPEUTICS INC COMMON STOCK USD.0001 |
NTLA
|
814 035 |
0.0 |
41 724 |
| MANNKIND CORP COMMON STOCK USD.01 |
MNKD
|
810 306 |
0.0 |
123 900 |
| DYNE THERAPEUTICS INC COMMON STOCK USD.0001 |
DYN
|
816 594 |
0.0 |
24 515 |
| KEROS THERAPEUTICS INC COMMON STOCK USD.0001 |
KROS
|
795 272 |
0.0 |
13 145 |
| NATIONAL HEALTHCARE CORP COMMON STOCK USD.01 |
NHC
|
771 897 |
0.0 |
6 373 |
| PRIVIA HEALTH GROUP INC COMMON STOCK USD.01 |
PRVA
|
783 500 |
0.0 |
44 116 |
| NOVOCURE LTD COMMON STOCK |
NVCR
|
753 792 |
0.0 |
46 936 |
| PATTERSON COS INC COMMON STOCK USD.01 |
PDCO
|
767 668 |
0.0 |
36 713 |
| RXSIGHT INC COMMON STOCK USD.001 |
RXST
|
759 076 |
0.0 |
15 103 |
| SCHOLAR ROCK HOLDING CORP COMMON STOCK USD.001 |
SRRK
|
760 685 |
0.0 |
26 672 |
| SPRINGWORKS THERAPEUTICS INC COMMON STOCK USD.0001 |
SWTX
|
767 005 |
0.0 |
25 189 |
| NOVAVAX INC COMMON STOCK USD.01 |
NVAX
|
724 249 |
0.0 |
57 389 |
| CLOVER HEALTH INVESTMENTS CO COMMON STOCK USD.0001 |
CLOV
|
727 266 |
0.0 |
176 521 |
| ACADIA PHARMACEUTICALS INC COMMON STOCK USD.0001 |
ACAD
|
726 025 |
0.0 |
48 434 |
| CAREDX INC COMMON STOCK USD.001 |
CDNA
|
708 889 |
0.0 |
22 641 |
| FORTREA HOLDINGS INC COMMON STOCK USD.001 |
FTRE
|
720 557 |
0.0 |
39 097 |
| IMMUNOVANT INC COMMON STOCK USD.0001 |
IMVT
|
701 702 |
0.0 |
23 835 |
| KYMERA THERAPEUTICS INC COMMON STOCK USD.0001 |
KYMR
|
709 768 |
0.0 |
15 413 |
| 10X GENOMICS INC CLASS A COMMON STOCK USD.00001 |
TXG
|
704 409 |
0.0 |
43 295 |
| AMN HEALTHCARE SERVICES INC COMMON STOCK USD.01 |
AMN
|
691 268 |
0.0 |
17 200 |
| HARROW INC COMMON STOCK USD.001 |
HROW
|
698 821 |
0.0 |
13 732 |
| SYNDAX PHARMACEUTICALS INC COMMON STOCK USD.0001 |
SNDX
|
688 725 |
0.0 |
34 749 |
| TELADOC HEALTH INC COMMON STOCK USD.001 |
TDOC
|
699 615 |
0.0 |
77 735 |
| VERA THERAPEUTICS INC COMMON STOCK USD.001 |
VERA
|
679 013 |
0.0 |
16 098 |
| AKERO THERAPEUTICS INC COMMON STOCK USD.0001 |
AKRO
|
663 791 |
0.0 |
22 119 |
| ARDELYX INC COMMON STOCK USD.000001 |
ARDX
|
633 592 |
0.0 |
105 775 |
| MIRUM PHARMACEUTICALS INC COMMON STOCK |
MIRM
|
641 887 |
0.0 |
16 140 |
| BIOCRYST PHARMACEUTICALS INC COMMON STOCK USD.01 |
BCRX
|
631 727 |
0.0 |
84 682 |
| NURIX THERAPEUTICS INC COMMON STOCK |
NRIX
|
628 924 |
0.0 |
24 997 |
| PROGYNY INC COMMON STOCK USD.0001 |
PGNY
|
621 083 |
0.0 |
39 484 |
| INTEGRA LIFESCIENCES HOLDING COMMON STOCK USD.01 |
IART
|
582 442 |
0.0 |
30 304 |
| VIRIDIAN THERAPEUTICS INC COMMON STOCK USD.01 |
VRDN
|
590 924 |
0.0 |
25 103 |
| TILRAY BRANDS INC COMMON STOCK USD.0001 |
TLRY
|
604 471 |
0.0 |
380 171 |
| XENCOR INC COMMON STOCK USD.01 |
XNCR
|
588 040 |
0.0 |
27 962 |
| DYNAVAX TECHNOLOGIES CORP COMMON STOCK USD.001 |
DVAX
|
585 341 |
0.0 |
55 960 |
| ATRICURE INC COMMON STOCK USD.001 |
ATRC
|
595 580 |
0.0 |
21 579 |
| US DOLLAR |
|
582 607 |
0.0 |
582 607 |
| ARVINAS INC COMMON STOCK USD.001 |
ARVN
|
558 296 |
0.0 |
21 749 |
| CERTARA INC COMMON STOCK USD.01 |
CERT
|
568 946 |
0.0 |
50 618 |
| COLLEGIUM PHARMACEUTICAL INC COMMON STOCK USD.001 |
COLL
|
560 006 |
0.0 |
14 737 |
| PACS GROUP INC COMMON STOCK USD.001 |
PACS
|
558 652 |
0.0 |
13 928 |
| RECURSION PHARMACEUTICALS A COMMON STOCK USD.00001 |
RXRX
|
561 422 |
0.0 |
83 545 |
| CASSAVA SCIENCES INC COMMON STOCK USD.001 |
SAVA
|
572 000 |
0.0 |
20 800 |
| STAAR SURGICAL CO COMMON STOCK USD.01 |
STAA
|
577 599 |
0.0 |
17 503 |
| U.S. PHYSICAL THERAPY INC COMMON STOCK USD.01 |
USPH
|
563 416 |
0.0 |
6 881 |
| EDGEWISE THERAPEUTICS INC COMMON STOCK USD.0001 |
EWTX
|
541 290 |
0.0 |
17 011 |
| SCHRODINGER INC COMMON STOCK USD.01 |
SDGR
|
512 024 |
0.0 |
28 717 |
| TRAVERE THERAPEUTICS INC COMMON STOCK USD.0001 |
TVTX
|
523 322 |
0.0 |
30 007 |
| PENNANT GROUP INC/THE COMMON STOCK USD.001 |
PNTG
|
531 973 |
0.0 |
15 291 |
| PHREESIA INC COMMON STOCK USD.01 |
PHR
|
530 734 |
0.0 |
25 237 |
| BROOKDALE SENIOR LIVING INC COMMON STOCK USD.01 |
BKD
|
514 637 |
0.0 |
85 064 |
| APOGEE THERAPEUTICS INC COMMON STOCK USD.00001 |
APGE
|
491 518 |
0.0 |
8 807 |
| HARMONY BIOSCIENCES HOLDINGS COMMON STOCK USD.00001 |
HRMY
|
496 755 |
0.0 |
14 001 |
| INNOVIVA INC COMMON STOCK USD.01 |
INVA
|
506 180 |
0.0 |
25 449 |
| PEDIATRIX MEDICAL GROUP INC COMMON STOCK USD.01 |
MD
|
486 907 |
0.0 |
39 586 |
| MOONLAKE IMMUNOTHERAPEUTICS COMMON STOCK USD.0001 |
MLTX
|
492 325 |
0.0 |
10 068 |
| OCULAR THERAPEUTIX INC COMMON STOCK USD.0001 |
OCUL
|
479 005 |
0.0 |
45 794 |
| AVANOS MEDICAL INC COMMON STOCK USD.01 |
AVNS
|
476 035 |
0.0 |
21 017 |
| ROCKET PHARMACEUTICALS INC COMMON STOCK USD.01 |
RCKT
|
486 686 |
0.0 |
28 798 |
| KINIKSA PHARMACEUTICALS INTE COMMON STOCK USD.000273 |
KNSA
|
485 358 |
0.0 |
18 226 |
| AMNEAL PHARMACEUTICALS INC COMMON STOCK USD.01 |
AMRX
|
483 496 |
0.0 |
55 831 |
| ALIGNMENT HEALTHCARE INC COMMON STOCK USD.001 |
ALHC
|
479 188 |
0.0 |
42 071 |
| AGILON HEALTH INC COMMON STOCK USD.01 |
AGL
|
483 780 |
0.0 |
138 223 |
| ANI PHARMACEUTICALS INC COMMON STOCK USD.0001 |
ANIP
|
460 219 |
0.0 |
7 867 |
| ARTIVION INC COMMON STOCK USD.01 |
AORT
|
452 945 |
0.0 |
17 288 |
| ARCUTIS BIOTHERAPEUTICS INC COMMON STOCK USD.0001 |
ARQT
|
458 715 |
0.0 |
47 096 |
| AVADEL PHARMACEUTICALS COMMON STOCK |
AVDL
|
462 701 |
0.0 |
35 133 |
| JANUX THERAPEUTICS INC COMMON STOCK USD.001 |
JANX
|
462 705 |
0.0 |
9 376 |
| OWENS & MINOR INC COMMON STOCK USD2.0 |
OMI
|
450 559 |
0.0 |
33 105 |
| SOLENO THERAPEUTICS INC COMMON STOCK USD.001 |
SLNO
|
454 309 |
0.0 |
8 435 |
| TARSUS PHARMACEUTICALS INC COMMON STOCK USD.0001 |
TARS
|
440 787 |
0.0 |
12 083 |
| BRIGHTSPRING HEALTH SERVICES COMMON STOCK USD100.0 |
BTSG
|
418 548 |
0.0 |
27 374 |
| MARAVAI LIFESCIENCES HLDGS A COMMON STOCK USD.01 |
MRVI
|
425 819 |
0.0 |
51 552 |
| ARCUS BIOSCIENCES INC COMMON STOCK USD.0001 |
RCUS
|
423 052 |
0.0 |
23 386 |
| AURINIA PHARMACEUTICALS INC COMMON STOCK |
AUPH
|
432 347 |
0.0 |
60 723 |
| LIFESTANCE HEALTH GROUP INC COMMON STOCK USD.01 |
LFST
|
435 814 |
0.0 |
61 124 |
| CASTLE BIOSCIENCES INC COMMON STOCK USD.001 |
CSTL
|
423 453 |
0.0 |
12 360 |
| ADAPTHEALTH CORP COMMON STOCK USD.0001 |
AHCO
|
396 100 |
0.0 |
39 531 |
| BIOLIFE SOLUTIONS INC COMMON STOCK USD.001 |
BLFS
|
403 355 |
0.0 |
17 208 |
| PRAXIS PRECISION MEDICINES I COMMON STOCK USD.0001 |
PRAX
|
411 134 |
0.0 |
5 870 |
| WAVE LIFE SCIENCES LTD COMMON STOCK |
WVE
|
411 898 |
0.0 |
47 182 |
| DISC MEDICINE INC COMMON STOCK USD.0001 |
IRON
|
390 254 |
0.0 |
8 132 |
| PETIQ INC COMMON STOCK USD.001 |
PETQ
|
388 902 |
0.0 |
12 594 |
| KURA ONCOLOGY INC COMMON STOCK USD.0001 |
KURA
|
376 785 |
0.0 |
20 863 |
| EVOLUS INC COMMON STOCK USD.00001 |
EOLS
|
370 073 |
0.0 |
21 466 |
| DAY ONE BIOPHARMACEUTICALS I COMMON STOCK USD.0001 |
DAWN
|
378 506 |
0.0 |
26 469 |
| ESTABLISHMENT LABS HOLDINGS COMMON STOCK USD1.0 |
ESTA
|
355 833 |
0.0 |
8 620 |
| RELAY THERAPEUTICS INC COMMON STOCK USD.001 |
RLAY
|
358 458 |
0.0 |
53 105 |
| SPYRE THERAPEUTICS INC COMMON STOCK USD.0001 |
SYRE
|
355 962 |
0.0 |
11 610 |
| COGENT BIOSCIENCES INC COMMON STOCK USD.001 |
COGT
|
320 728 |
0.0 |
28 358 |
| EMBECTA CORP COMMON STOCK USD.01 |
EMBC
|
335 444 |
0.0 |
25 626 |
| PACIRA BIOSCIENCES INC COMMON STOCK USD.001 |
PCRX
|
339 537 |
0.0 |
20 805 |
| VIR BIOTECHNOLOGY INC COMMON STOCK |
VIR
|
326 312 |
0.0 |
42 544 |
| MESA LABORATORIES INC COMMON STOCK |
MLAB
|
301 192 |
0.0 |
2 343 |
| PLIANT THERAPEUTICS INC COMMON STOCK |
PLRX
|
310 366 |
0.0 |
22 605 |
| COMMUNITY HEALTH SYSTEMS INC COMMON STOCK USD.01 |
CYH
|
318 674 |
0.0 |
57 008 |
| MIMEDX GROUP INC COMMON STOCK USD.001 |
MDXG
|
318 639 |
0.0 |
55 609 |
| HEALTHSTREAM INC COMMON STOCK |
HSTM
|
313 703 |
0.0 |
11 081 |
| AVID BIOSERVICES INC COMMON STOCK USD.001 |
CDMO
|
283 508 |
0.0 |
27 987 |
| CULLINAN THERAPEUTICS INC COMMON STOCK USD.0001 |
CGEM
|
282 353 |
0.0 |
17 397 |
| CG ONCOLOGY INC COMMON STOCK |
CGON
|
286 127 |
0.0 |
7 626 |
| CYTEK BIOSCIENCES INC COMMON STOCK USD.001 |
CTKB
|
280 326 |
0.0 |
52 693 |
| IRONWOOD PHARMACEUTICALS INC COMMON STOCK USD.001 |
IRWD
|
277 597 |
0.0 |
64 708 |
| PROTHENA CORP PLC COMMON STOCK USD.01 |
PRTA
|
274 885 |
0.0 |
15 871 |
| GENEDX HOLDINGS CORP COMMON STOCK USD.0001 |
WGS
|
285 127 |
0.0 |
4 772 |
| GOODRX HOLDINGS INC CLASS A COMMON STOCK USD.0001 |
GDRX
|
250 197 |
0.0 |
36 208 |
| ZYMEWORKS INC COMMON STOCK USD.00001 |
ZYME
|
262 182 |
0.0 |
19 713 |
| ARS PHARMACEUTICALS INC COMMON STOCK USD.0001 |
SPRY
|
249 814 |
0.0 |
16 710 |
| PHATHOM PHARMACEUTICALS INC COMMON STOCK USD.0001 |
PHAT
|
261 914 |
0.0 |
17 141 |
| ALPHATEC HOLDINGS INC COMMON STOCK USD.0001 |
ATEC
|
254 923 |
0.0 |
47 918 |
| 89BIO INC COMMON STOCK USD.001 |
ETNB
|
250 762 |
0.0 |
31 702 |
| PERSPECTIVE THERAPEUTICS INC COMMON STOCK USD.001 |
CATX
|
265 095 |
0.0 |
21 570 |
| ARBUTUS BIOPHARMA CORP COMMON STOCK |
ABUS
|
249 641 |
0.0 |
64 674 |
| OPKO HEALTH INC COMMON STOCK USD.01 |
OPK
|
233 200 |
0.0 |
158 640 |
| SIMULATIONS PLUS INC COMMON STOCK USD.001 |
SLP
|
242 467 |
0.0 |
7 644 |
| SI BONE INC COMMON STOCK USD.0001 |
SIBN
|
226 682 |
0.0 |
17 304 |
| PHIBRO ANIMAL HEALTH CORP A COMMON STOCK USD.001 |
PAHC
|
226 698 |
0.0 |
9 333 |
| REVANCE THERAPEUTICS INC COMMON STOCK USD.001 |
RVNC
|
237 740 |
0.0 |
46 253 |
| ORTHOFIX MEDICAL INC COMMON STOCK USD.1 |
OFIX
|
244 365 |
0.0 |
15 178 |
| ARCTURUS THERAPEUTICS HOLDIN COMMON STOCK USD.001 |
ARCT
|
227 484 |
0.0 |
10 874 |
| EYEPOINT PHARMACEUTICALS INC COMMON STOCK USD.01 |
EYPT
|
228 275 |
0.0 |
22 446 |
| ENLIVEN THERAPEUTICS INC COMMON STOCK USD.001 |
ELVN
|
237 207 |
0.0 |
8 548 |
| IMMUNITYBIO INC COMMON STOCK USD.0001 |
IBRX
|
230 714 |
0.0 |
62 020 |
| STANDARD BIOTOOLS INC COMMON STOCK USD.001 |
LAB
|
213 896 |
0.0 |
113 173 |
| Y MABS THERAPEUTICS INC COMMON STOCK USD.0001 |
YMAB
|
202 978 |
0.0 |
13 960 |
| VAREX IMAGING CORP COMMON STOCK USD.01 |
VREX
|
207 339 |
0.0 |
18 300 |
| PACIFIC BIOSCIENCES OF CALIF COMMON STOCK USD.0001 |
PACB
|
222 386 |
0.0 |
108 481 |
| LIQUIDIA CORP COMMON STOCK USD.001 |
LQDA
|
221 965 |
0.0 |
19 934 |
| SANA BIOTECHNOLOGY INC COMMON STOCK USD.0001 |
SANA
|
213 652 |
0.0 |
53 280 |
| IMMUNOME INC COMMON STOCK USD.0001 |
IMNM
|
222 515 |
0.0 |
18 314 |
| HUMACYTE INC COMMON STOCK USD.0001 |
HUMA
|
215 845 |
0.0 |
38 068 |
| ERASCA INC COMMON STOCK USD.0001 |
ERAS
|
212 143 |
0.0 |
77 143 |
| ANAPTYSBIO INC COMMON STOCK USD.001 |
ANAB
|
214 067 |
0.0 |
6 162 |
| ALTIMMUNE INC COMMON STOCK USD.0001 |
ALT
|
207 361 |
0.0 |
32 249 |
| CROSS COUNTRY HEALTHCARE INC COMMON STOCK USD.0001 |
CCRN
|
195 288 |
0.0 |
15 903 |
| ORTHOPEDIATRICS CORP COMMON STOCK USD.00025 |
KIDS
|
200 282 |
0.0 |
7 718 |
| QUANTERIX CORP COMMON STOCK USD.001 |
QTRX
|
199 789 |
0.0 |
16 336 |
| REGENXBIO INC COMMON STOCK USD.0001 |
RGNX
|
191 964 |
0.0 |
18 820 |
| UROGEN PHARMA LTD COMMON STOCK USD.01 |
URGN
|
161 488 |
0.0 |
13 172 |
| SAVARA INC COMMON STOCK USD.001 |
SVRA
|
164 509 |
0.0 |
44 948 |
| NUVATION BIO INC COMMON STOCK USD.0001 |
NUVB
|
162 442 |
0.0 |
70 627 |
| STOKE THERAPEUTICS INC COMMON STOCK |
STOK
|
167 130 |
0.0 |
13 098 |
| REPLIMUNE GROUP INC COMMON STOCK USD.001 |
REPL
|
164 616 |
0.0 |
15 428 |
| OLEMA PHARMACEUTICALS INC COMMON STOCK USD.0001 |
OLMA
|
170 519 |
0.0 |
14 537 |
| OMNIAB INC COMMON STOCK USD.0001 |
OABI
|
162 758 |
0.0 |
40 997 |
| CRYOPORT INC COMMON STOCK USD.001 |
CYRX
|
157 815 |
0.0 |
22 134 |
| NEWAMSTERDAM PHARMA CO NV COMMON STOCK |
NAMS
|
155 694 |
0.0 |
8 126 |
| IRADIMED CORP COMMON STOCK USD.0001 |
IRMD
|
169 192 |
0.0 |
3 359 |
| GRAIL INC COMMON STOCK |
GRAL
|
167 105 |
0.0 |
12 048 |
| FULGENT GENETICS INC COMMON STOCK USD.0001 |
FLGT
|
171 448 |
0.0 |
8 425 |
| ALLOGENE THERAPEUTICS INC COMMON STOCK USD.001 |
ALLO
|
174 931 |
0.0 |
66 514 |
| ALECTOR INC COMMON STOCK USD.0001 |
ALEC
|
157 476 |
0.0 |
32 138 |
| MAXCYTE INC COMMON STOCK |
MXCT
|
173 987 |
0.0 |
44 958 |
| PULSE BIOSCIENCES INC COMMON STOCK USD.001 |
PLSE
|
138 850 |
0.0 |
8 405 |
| VERVE THERAPEUTICS INC COMMON STOCK USD.001 |
VERV
|
141 871 |
0.0 |
28 205 |
| TYRA BIOSCIENCES INC COMMON STOCK USD.0001 |
TYRA
|
132 494 |
0.0 |
6 017 |
| TANGO THERAPEUTICS INC COMMON STOCK USD.0001 |
TNGX
|
142 470 |
0.0 |
20 829 |
| THERAVANCE BIOPHARMA INC COMMON STOCK USD.00001 |
TBPH
|
130 766 |
0.0 |
15 889 |
| SIGA TECHNOLOGIES INC COMMON STOCK USD.0001 |
SIGA
|
138 172 |
0.0 |
20 470 |
| SAGE THERAPEUTICS INC COMMON STOCK USD.0001 |
SAGE
|
139 856 |
0.0 |
20 537 |
| ENTRADA THERAPEUTICS INC COMMON STOCK USD.0001 |
TRDA
|
148 702 |
0.0 |
8 340 |
| ORIC PHARMACEUTICALS INC COMMON STOCK USD.0001 |
ORIC
|
146 200 |
0.0 |
15 325 |
| MIND MEDICINE MINDMED INC COMMON STOCK |
MNMD
|
148 991 |
0.0 |
25 644 |
| LEXICON PHARMACEUTICALS INC COMMON STOCK USD.001 |
LXRX
|
133 034 |
0.0 |
74 321 |
| ENHABIT INC COMMON STOCK USD.01 |
EHAB
|
137 643 |
0.0 |
19 224 |
| CARGO THERAPEUTICS INC COMMON STOCK USD.001 |
CRGX
|
133 396 |
0.0 |
6 581 |
| ASTRIA THERAPEUTICS INC COMMON STOCK USD.001 |
ATXS
|
152 699 |
0.0 |
13 794 |
| NATIONAL RESEARCH CORP COMMON STOCK USD.001 |
NRC
|
131 452 |
0.0 |
6 904 |
| EDITAS MEDICINE INC COMMON STOCK USD.0001 |
EDIT
|
122 588 |
0.0 |
37 836 |
| FATE THERAPEUTICS INC COMMON STOCK USD.001 |
FATE
|
126 385 |
0.0 |
41 438 |
| PARAGON 28 INC COMMON STOCK USD.01 |
FNA
|
123 495 |
0.0 |
20 686 |
| TREACE MEDICAL CONCEPTS INC COMMON STOCK USD.001 |
TMCI
|
107 187 |
0.0 |
20 613 |
| 4D MOLECULAR THERAPEUTICS IN COMMON STOCK USD.0001 |
FDMT
|
103 962 |
0.0 |
11 513 |
| ITEOS THERAPEUTICS INC COMMON STOCK USD.001 |
ITOS
|
99 839 |
0.0 |
10 261 |
| DIANTHUS THERAPEUTICS INC COMMON STOCK USD.001 |
DNTH
|
101 796 |
0.0 |
4 003 |
| DEFINITIVE HEALTHCARE CORP COMMON STOCK USD.001 |
DH
|
102 137 |
0.0 |
23 108 |
| LYELL IMMUNOPHARMA INC COMMON STOCK USD.0001 |
LYEL
|
65 975 |
0.0 |
55 442 |
| XAV HEALTH CARE DEC24 XCME 20241220 |
XAVZ24
|
-55 071 |
0.0 |
4 500 |
| CONTRA SCILEX HLDG CO COMMON STOCK |
|
21 980 |
0.0 |
34 921 |
| E-MINI RUSS 2000 DEC24 XCME 20241220 |
RTYZ24
|
13 572 |
0.0 |
250 |
| CONTRA AKOUOS INC COMMON STOCK |
|
2 135 |
0.0 |
11 863 |
| CONTRA CHINOOK THERAPE COMMON STOCK |
|
0 |
0.0 |
24 218 |
| RADIUS HEALTH I COMMON STOCK |
|
0 |
0.0 |
20 244 |
| OMNIAB INC 12.5 EARNOUT COMMON STOCK |
2200963D
|
9 538 |
0.0 |
3 335 |
| OMNIAB INC 15.00 EARNOUT COMMON STOCK |
2200964D
|
8 737 |
0.0 |
3 335 |
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