| ARGENX |
ARGX
|
22 770 700 |
2.0 |
43 568 |
| UCB SA |
UCBJF
|
21 842 534 |
1.9 |
116 595 |
| GILEAD SCIENCES INC |
GILD
|
21 398 541 |
1.8 |
255 383 |
| SAMSUNG BIOLOGICS LTD |
207940.KS
|
21 057 172 |
1.8 |
25 977 |
| INSULET CORP |
PODD
|
20 516 140 |
1.8 |
85 838 |
| BRISTOL MYERS SQUIBB |
BMY
|
19 529 173 |
1.7 |
383 376 |
| ABBVIE INC |
ABBV
|
19 122 077 |
1.7 |
98 817 |
| INTUITIVE SURGICAL INC |
ISRG
|
18 994 292 |
1.6 |
39 212 |
| LONZA GROUP AG |
LZAGF
|
18 897 230 |
1.6 |
29 933 |
| ILLUMINA INC |
ILMN
|
18 835 287 |
1.6 |
146 214 |
| ROCHE HOLDING PAR AG |
ROG
|
18 694 170 |
1.6 |
58 543 |
| NOVARTIS AG |
NOVN
|
18 428 821 |
1.6 |
158 254 |
| JOHNSON & JOHNSON |
JNJ
|
18 387 628 |
1.6 |
112 960 |
| IQVIA HOLDINGS INC |
IQV
|
18 337 646 |
1.6 |
76 544 |
| HOLOGIC INC |
HOLX
|
18 307 332 |
1.6 |
225 432 |
| AMGEN INC |
AMGN
|
18 218 469 |
1.6 |
55 054 |
| CELLTRION INC |
068270.KS
|
18 066 233 |
1.6 |
117 347 |
| MEDTRONIC PLC |
MDT
|
18 001 996 |
1.6 |
200 557 |
| NATERA INC |
NTRA
|
17 980 264 |
1.6 |
146 086 |
| EXACT SCIENCES CORP |
EXAS
|
17 816 190 |
1.5 |
259 220 |
| BOSTON SCIENTIFIC CORP |
BSX
|
17 791 889 |
1.5 |
213 051 |
| AGILENT TECHNOLOGIES INC |
A
|
17 728 500 |
1.5 |
124 963 |
| ABBOTT LABORATORIES |
ABT
|
17 579 487 |
1.5 |
155 104 |
| THERMO FISHER SCIENTIFIC INC |
TMO
|
17 554 837 |
1.5 |
28 690 |
| PFIZER INC |
PFE
|
17 435 208 |
1.5 |
591 024 |
| DANAHER CORP |
DHR
|
17 268 841 |
1.5 |
62 979 |
| SAREPTA THERAPEUTICS INC |
SRPT
|
16 780 020 |
1.5 |
133 716 |
| BIO TECHNE CORP |
TECH
|
16 632 370 |
1.4 |
214 833 |
| GLAXOSMITHKLINE |
GSK
|
16 543 069 |
1.4 |
807 420 |
| BEIGENE LTD |
6160.HK
|
15 679 539 |
1.4 |
979 600 |
| CATALENT INC |
CTLT
|
15 461 212 |
1.3 |
257 087 |
| EISAI LTD |
4523.T
|
15 212 350 |
1.3 |
391 200 |
| CHARLES RIVER LABORATORIES INTERNA |
CRL
|
14 683 979 |
1.3 |
73 193 |
| SYSMEX CORP |
6869.T
|
14 625 236 |
1.3 |
746 326 |
| GENMAB |
GMAB
|
14 552 834 |
1.3 |
60 533 |
| MERCK & CO INC |
MRK
|
14 471 279 |
1.3 |
125 881 |
| NEUROCRINE BIOSCIENCES INC |
NBIX
|
14 472 834 |
1.3 |
124 241 |
| QIAGEN NV |
QGEN
|
14 420 968 |
1.2 |
320 110 |
| BIOGEN INC |
BIIB
|
14 257 725 |
1.2 |
73 448 |
| SHIMADZU CORP |
7701.T
|
13 980 415 |
1.2 |
424 300 |
| EDWARDS LIFESCIENCES CORP |
EW
|
12 524 364 |
1.1 |
188 819 |
| MEDPACE HOLDINGS INC |
MEDP
|
11 656 307 |
1.0 |
32 759 |
| EXELIXIS INC |
EXEL
|
11 441 050 |
1.0 |
435 352 |
| LANTHEUS HOLDINGS INC |
LNTH
|
10 906 211 |
0.9 |
97 586 |
| REPLIGEN CORP |
RGEN
|
10 668 752 |
0.9 |
74 685 |
| HALOZYME THERAPEUTICS INC |
HALO
|
10 652 091 |
0.9 |
189 539 |
| BIO RAD LABORATORIES INC CLASS A |
BIO
|
10 442 312 |
0.9 |
31 847 |
| REVOLUTION MEDICINES INC |
RVMD
|
10 330 681 |
0.9 |
232 673 |
| ZEALAND PHARMA |
ZEAL
|
10 187 977 |
0.9 |
80 190 |
| INTRA CELLULAR THERAPIES INC |
ITCI
|
9 803 855 |
0.8 |
129 818 |
| DEXCOM INC |
DXCM
|
9 689 917 |
0.8 |
141 129 |
| SARTORIUS PREF AG |
SUVPF
|
9 333 039 |
0.8 |
35 906 |
| PRO MEDICUS LTD |
PME
|
9 223 181 |
0.8 |
76 677 |
| IONIS PHARMACEUTICALS INC |
IONS
|
8 456 783 |
0.7 |
206 263 |
| BIOMERIEUX SA |
BMXMF
|
8 447 376 |
0.7 |
70 208 |
| MAXIMUS INC |
MMS
|
8 072 341 |
0.7 |
87 934 |
| SIEGFRIED HOLDING AG |
SFZN.SW
|
7 348 709 |
0.6 |
5 443 |
| MODERNA INC |
MRNA
|
7 106 739 |
0.6 |
111 147 |
| ALKERMES |
ALKS
|
6 611 497 |
0.6 |
241 560 |
| ASAHI INTECC LTD |
7747.T
|
6 524 781 |
0.6 |
361 600 |
| IPSEN SA |
IPSEF
|
6 501 530 |
0.6 |
52 291 |
| TECAN GROUP AG |
TCHBF
|
5 780 761 |
0.5 |
18 396 |
| SECTRA CLASS B |
0A0L.IL
|
5 507 617 |
0.5 |
211 856 |
| DENALI THERAPEUTICS INC |
DNLI
|
5 408 511 |
0.5 |
178 381 |
| NEOGEN CORP |
NEOG
|
5 218 023 |
0.5 |
307 848 |
| BRIDGEBIO PHARMA INC |
BBIO
|
5 016 499 |
0.4 |
201 790 |
| AXSOME THERAPEUTICS INC |
AXSM
|
4 889 467 |
0.4 |
53 548 |
| AXONICS INC |
AXNX
|
4 716 744 |
0.4 |
68 102 |
| AKESO INC |
9926.HK
|
4 694 015 |
0.4 |
601 000 |
| CORVEL CORP |
CRVL
|
4 653 754 |
0.4 |
14 528 |
| TG THERAPEUTICS INC |
TGTX
|
4 628 899 |
0.4 |
198 580 |
| EVOLENT HEALTH INC CLASS A |
EVH
|
4 483 660 |
0.4 |
151 680 |
| DIASORIN |
DIA
|
4 353 921 |
0.4 |
38 130 |
| TANDEM DIABETES CARE INC |
TNDM
|
4 257 455 |
0.4 |
93 694 |
| ARCELLX INC |
ACLX
|
4 045 027 |
0.4 |
47 907 |
| LIVANOVA PLC |
LIVN
|
4 046 276 |
0.4 |
78 599 |
| R1 RCM INC |
RCM
|
4 016 251 |
0.3 |
283 834 |
| PTC THERAPEUTICS INC |
PTCT
|
3 986 559 |
0.3 |
109 161 |
| RHYTHM PHARMACEUTICALS INC |
RYTM
|
3 970 690 |
0.3 |
77 492 |
| GUARDANT HEALTH INC |
GH
|
3 906 850 |
0.3 |
173 176 |
| BAVARIAN NORDIC |
BAVA.CO
|
3 862 766 |
0.3 |
111 089 |
| BACHEM HOLDING AG |
BCHMF
|
3 801 813 |
0.3 |
45 776 |
| MERUS NV |
MRUS
|
3 610 011 |
0.3 |
75 761 |
| GERON CORP |
GERN
|
3 587 549 |
0.3 |
779 902 |
| TWIST BIOSCIENCE CORP |
TWST
|
3 586 758 |
0.3 |
77 201 |
| ELEKTA B |
EKTA-B.ST
|
3 584 261 |
0.3 |
543 233 |
| VERACYTE INC |
VCYT
|
3 532 273 |
0.3 |
104 722 |
| CATALYST PHARMACEUTICALS INC |
CPRX
|
3 496 664 |
0.3 |
170 569 |
| SK BIOPHARMACEUTICALS LTD |
326030.KS
|
3 408 214 |
0.3 |
41 170 |
| 10X GENOMICS INC CLASS A |
TXG
|
3 400 593 |
0.3 |
148 045 |
| MYRIAD GENETICS INC |
MYGN
|
3 374 611 |
0.3 |
127 104 |
| IDEAYA BIOSCIENCES INC |
IDYA
|
3 323 745 |
0.3 |
105 953 |
| QUIDELORTHO CORP |
QDEL
|
3 229 271 |
0.3 |
71 145 |
| ASTRANA HEALTH INC |
ASTH
|
3 177 897 |
0.3 |
57 177 |
| IOVANCE BIOTHERAPEUTICS INC |
IOVA
|
3 008 021 |
0.3 |
322 058 |
| JEOL LTD |
6951.T
|
2 827 718 |
0.2 |
74 300 |
| FORTREA HOLDINGS INC |
FTRE
|
2 793 662 |
0.2 |
125 784 |
| SAWAI GROUP HOLDINGS LTD |
4887.T
|
2 783 532 |
0.2 |
63 000 |
| ACADIA PHARMACEUTICALS INC |
ACAD
|
2 734 934 |
0.2 |
172 660 |
| H. LUNDBECK CLASS B |
HLUN-B.CO
|
2 582 708 |
0.2 |
390 528 |
| HUTCHMED (CHINA) LTD |
0013.HK
|
2 567 585 |
0.2 |
750 000 |
| BEAM THERAPEUTICS INC |
BEAM
|
2 486 041 |
0.2 |
100 365 |
| LIGAND PHARMACEUTICALS INC |
LGND
|
2 465 506 |
0.2 |
24 769 |
| JANUX THERAPEUTICS INC |
JANX
|
2 434 392 |
0.2 |
50 111 |
| SUPERNUS PHARMACEUTICALS INC |
SUPN
|
2 402 435 |
0.2 |
78 588 |
| NOVOCURE LTD |
NVCR
|
2 333 963 |
0.2 |
142 055 |
| BIOCRYST PHARMACEUTICALS INC |
BCRX
|
2 268 811 |
0.2 |
297 354 |
| ARVINAS INC |
ARVN
|
2 218 281 |
0.2 |
89 700 |
| NOVAVAX INC |
NVAX
|
2 139 756 |
0.2 |
161 005 |
| CAREDX INC |
CDNA
|
2 093 004 |
0.2 |
72 927 |
| HARMONY BIOSCIENCES HLDG INC |
HRMY
|
2 068 224 |
0.2 |
54 686 |
| ATRICURE INC |
ATRC
|
2 036 444 |
0.2 |
69 032 |
| DYNAVAX TECHNOLOGIES CORP |
DVAX
|
2 009 721 |
0.2 |
184 887 |
| OXFORD NANOPORE TECHNOLOGIES PLC |
ONTTF
|
1 913 215 |
0.2 |
926 822 |
| E-MINI HEALTH CARE SECTOR DEC 24 |
IXCZ4
|
1 887 360 |
0.2 |
12 |
| NEUREN PHARMACEUTICALS LTD |
NEU
|
1 785 340 |
0.2 |
186 211 |
| THE UNITED LABORATORIES INTERNATIO |
3933.HK
|
1 741 513 |
0.2 |
1 498 000 |
| INTEGRA LIFESCIENCES HOLDINGS CORP |
IART
|
1 737 363 |
0.2 |
97 168 |
| CERTARA INC |
CERT
|
1 689 925 |
0.1 |
157 937 |
| XENCOR INC |
XNCR
|
1 673 004 |
0.1 |
82 781 |
| RECURSION PHARMACEUTICALS INC CLAS |
RXRX
|
1 667 427 |
0.1 |
243 776 |
| XVIVO PERFUSION |
XVIVO.ST
|
1 668 971 |
0.1 |
33 828 |
| GALAPAGOS NV |
GLPG
|
1 637 279 |
0.1 |
56 822 |
| PROTHENA PLC |
PRTA
|
1 597 705 |
0.1 |
72 557 |
| SCHRODINGER INC |
SDGR
|
1 573 387 |
0.1 |
83 204 |
| CHEMOMETEC |
CHEMM.CO
|
1 542 945 |
0.1 |
25 163 |
| SK BIOSCIENCE LTD |
302440.KS
|
1 500 615 |
0.1 |
36 221 |
| EVOTEC |
EVT
|
1 405 878 |
0.1 |
213 147 |
| AURINIA PHARMACEUTICALS INC |
AUPH
|
1 400 595 |
0.1 |
199 515 |
| MARAVAI LIFESCIENCES HOLDINGS INC |
MRVI
|
1 372 457 |
0.1 |
162 421 |
| RELAY THERAPEUTICS INC |
RLAY
|
1 296 096 |
0.1 |
177 791 |
| SEEGENE INC |
096530.KQ
|
1 265 549 |
0.1 |
67 301 |
| ABL BIO INC |
298380.KQ
|
1 227 509 |
0.1 |
51 043 |
| ST PHARM LTD |
237690.KQ
|
1 177 149 |
0.1 |
14 455 |
| ZYMEWORKS INC |
ZYME
|
1 163 037 |
0.1 |
93 043 |
| VIR BIOTECHNOLOGY INC |
VIR
|
1 154 464 |
0.1 |
153 112 |
| CASTLE BIOSCIENCES INC |
CSTL
|
1 142 505 |
0.1 |
39 060 |
| AVID BIOSERVICES INC |
CDMO
|
1 116 289 |
0.1 |
96 149 |
| RUSSELL 2000 EMINI CME DEC 24 |
RTYZ4
|
1 123 250 |
0.1 |
10 |
| LUNIT INC |
328130.KQ
|
1 115 970 |
0.1 |
33 893 |
| KEYMED BIOSCIENCES INC |
2162.HK
|
1 025 454 |
0.1 |
225 500 |
| PHARMA MAR SA |
PHM
|
1 010 915 |
0.1 |
19 471 |
| PEPTRON INC |
087010.KQ
|
993 764 |
0.1 |
24 887 |
| CYTEK BIOSCIENCES INC |
CTKB
|
957 827 |
0.1 |
183 844 |
| ARCUS BIOSCIENCES INC |
RCUS
|
951 615 |
0.1 |
61 001 |
| IMMUNITYBIO INC |
IBRX
|
953 874 |
0.1 |
264 965 |
| BIOARCTIC CLASS B |
BIOA-B.ST
|
927 158 |
0.1 |
58 303 |
| POLARIS GROUP |
6550.TW
|
877 858 |
0.1 |
516 000 |
| ANAPTYSBIO INC |
ANAB
|
884 312 |
0.1 |
25 353 |
| AXOGEN INC |
AXGN
|
870 707 |
0.1 |
60 592 |
| USD CASH |
|
820 897 |
0.1 |
820 898 |
| ABCELLERA BIOLOGICS INC |
ABCL
|
802 607 |
0.1 |
318 495 |
| ROCHE HOLDING AG |
RHHBF
|
793 417 |
0.1 |
2 340 |
| DYNAVOX GROUP |
TDVOX.ST
|
764 658 |
0.1 |
132 335 |
| EIKEN CHEMICAL LTD |
4549.T
|
734 947 |
0.1 |
44 800 |
| JAPAN LIFELINE LTD |
7575.T
|
737 865 |
0.1 |
86 400 |
| ADAPTIVE BIOTECHNOLOGIES CORP |
ADPT
|
741 463 |
0.1 |
177 809 |
| Y MABS THERAPEUTICS INC |
YMAB
|
723 477 |
0.1 |
55 867 |
| 4D MOLECULAR THERAPEUTICS INC |
FDMT
|
725 306 |
0.1 |
63 125 |
| PHARMING GROUP NV |
PHGUF
|
727 360 |
0.1 |
945 337 |
| ARCTURUS THERAPEUTICS HOLDINGS INC |
ARCT
|
714 985 |
0.1 |
32 888 |
| QUANTERIX CORP |
QTRX
|
713 737 |
0.1 |
51 422 |
| SIMULATIONS PLUS INC |
SLP
|
707 406 |
0.1 |
22 572 |
| PACIFIC BIOSCIENCES OF CALIFORNIA |
PACB
|
679 618 |
0.1 |
392 843 |
| REGENXBIO INC |
RGNX
|
645 696 |
0.1 |
57 600 |
| ALECTOR INC |
ALEC
|
619 132 |
0.1 |
119 064 |
| COMPUGROUP MEDICAL N |
COP
|
594 221 |
0.1 |
39 561 |
| SAGE THERAPEUTICS INC |
SAGE
|
580 348 |
0.0 |
79 391 |
| SD BIOSENSOR INC |
137310.KS
|
555 294 |
0.0 |
78 768 |
| ITEOS THERAPEUTICS INC |
ITOS
|
533 526 |
0.0 |
52 668 |
| STOKE THERAPEUTICS INC |
STOK
|
521 485 |
0.0 |
40 551 |
| SHINPOONG PHARMACEUTICAL LTD |
019170.KS
|
522 925 |
0.0 |
55 662 |
| TAKARA BIO INC |
4974.T
|
507 176 |
0.0 |
71 300 |
| FATE THERAPEUTICS INC |
FATE
|
512 839 |
0.0 |
148 649 |
| ALLOGENE THERAPEUTICS INC |
ALLO
|
513 892 |
0.0 |
192 469 |
| ORASURE TECHNOLOGIES INC |
OSUR
|
481 032 |
0.0 |
111 868 |
| UROGEN PHARMA LTD |
URGN
|
460 560 |
0.0 |
35 265 |
| VANDA PHARMACEUTICALS INC |
VNDA
|
422 711 |
0.0 |
85 224 |
| CHF CASH |
|
418 654 |
0.0 |
354 119 |
| EUR CASH |
|
410 552 |
0.0 |
368 176 |
| VALNEVA |
INRLF
|
399 479 |
0.0 |
136 008 |
| SILLAJEN INC |
215600.KQ
|
396 935 |
0.0 |
187 219 |
| LYELL IMMUNOPHARMA INC |
LYEL
|
391 690 |
0.0 |
268 281 |
| REMEGEN LTD H |
9995.HK
|
373 189 |
0.0 |
253 500 |
| ACCOLADE INC |
ACCD
|
365 253 |
0.0 |
93 177 |
| MERSANA THERAPEUTICS INC |
MRSN
|
358 214 |
0.0 |
190 034 |
| SHANGHAI JUNSHI BIOSCIENCES LTD H |
1877.HK
|
332 287 |
0.0 |
232 200 |
| I-SENS INC |
099190.KQ
|
320 678 |
0.0 |
24 671 |
| PHC HOLDINGS CORP |
6523.T
|
308 665 |
0.0 |
40 500 |
| NEVRO CORP |
NVRO
|
313 358 |
0.0 |
54 592 |
| GBP CASH |
|
301 498 |
0.0 |
225 218 |
| VENUS MEDTECH HANGZHOU INC H |
2500.HK
|
305 546 |
0.0 |
539 000 |
| IDORSIA N LTD |
IDRSF
|
295 692 |
0.0 |
183 232 |
| ATAI LIFE SCIENCES N V NV |
ATAI
|
290 143 |
0.0 |
245 884 |
| SUTRO BIOPHARMA INC |
STRO
|
286 089 |
0.0 |
84 144 |
| JPY CASH |
|
274 282 |
0.0 |
39 407 546 |
| KRW CASH |
|
265 819 |
0.0 |
354 815 699 |
| MACROGENICS INC |
MGNX
|
255 924 |
0.0 |
85 308 |
| SEK CASH |
|
241 878 |
0.0 |
2 448 836 |
| UNIQURE NV |
QURE
|
221 374 |
0.0 |
43 069 |
| CELLIVERY THERAPEUTICS INC |
268600.KQ
|
220 710 |
0.0 |
67 850 |
| CARIBOU BIOSCIENCES INC |
CRBU
|
191 448 |
0.0 |
99 713 |
| DKK CASH |
|
179 867 |
0.0 |
1 202 676 |
| NKMAX LTD |
182400.KQ
|
170 062 |
0.0 |
132 724 |
| CASH COLLATERAL USD HSBFT |
HSBFT
|
172 000 |
0.0 |
172 000 |
| AGENUS INC |
AGEN
|
134 549 |
0.0 |
26 025 |
| HKD CASH |
|
127 674 |
0.0 |
993 886 |
| AUD CASH |
|
75 071 |
0.0 |
109 306 |
| INR CASH |
|
45 681 |
0.0 |
3 822 078 |
| CNY CASH |
|
34 189 |
0.0 |
240 640 |
| NOK CASH |
|
24 025 |
0.0 |
250 554 |
| TWD CASH |
|
19 414 |
0.0 |
620 798 |
| TWD/USD |
|
0 |
0.0 |
-110 400 |
| JPY/USD |
|
-2 |
0.0 |
-29 716 950 |
| SEK/USD |
|
0 |
0.0 |
-447 551 |
| OMNIAB INC $15.00 VESTING Prvt |
|
0 |
0.0 |
14 172 |
| OMNIAB INC $12.50 VESTING Prvt |
|
0 |
0.0 |
14 172 |
| KRW/USD |
|
13 |
0.0 |
-240 968 300 |
| CHF/USD |
|
-2 |
0.0 |
-218 154 |
| ILS CASH |
|
879 |
0.0 |
3 301 |
| HKD/USD |
|
0 |
0.0 |
-711 338 |
| GBP/USD |
|
0 |
0.0 |
-48 481 |
| EUR/USD |
|
-2 |
0.0 |
-290 877 |
| DKK/USD |
|
-1 |
0.0 |
-802 789 |
| AUD/USD |
|
0 |
0.0 |
-55 418 |
| FUTURES GBP MARGIN BALANCE |
MARGIN_GBP
|
0 |
0.0 |
0 |
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